Hematological complications in the newborn: focus on perinatal hemolytic disease
Keywords:
alloantibodies, hemolytic disease of the newborn, Exchange transfusionAbstract
Introduction: Perinatal hemolytic disease is an immunological condition in which maternal antibodies cross the placenta and cause hemolysis in the fetus or newborn.
Objective: To present a case diagnosed with perinatal hemolytic disease with multiple alloimmunization.
Clinical Case: We present the case of a newborn with perinatal hemolytic disease due to the presence of two alloantibodies, anti-D and anti-Lewis. The mother, with a history of previous pregnancies and blood transfusion, showed a high titer of both antibodies during the third. trimester. The newborn required intensive phototherapy and exchange transfusion.
Conclusions: It is essential to conduct serological monitoring in pregnant women at risk of alloimmunization, as well as to have a multidisciplinary approach to prevent severe complications.
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