Clinical evolution of the functional capability in patients with systemic sclerosis treated with cyclophosphamide and reduce dose of steroids
Abstract
Introduction. The systemic sclerosis is an autoimmune disease of the connective tissue where the vasculopathy happens initially and persist during all the disease. The functional capability (FC), the commitment of the system reveals muscleskeletic of the patient, than little lime or incapacities of temporary form or permanent the realization of certain shows, measurable with the instrument of evaluation. Methods. The questionnaire that was utilized is the Cochin Hand Function scale (CHFS), measure the degree of disability of the hands. The patients split into two groups according to the clinical stages obtained in previous published study. In the group A (clinical stages I and II) they included 16 patients and 15 patients (clinical stages III and IV) included B themselves in the group, (annex 2). Results. The applied medical treatment, previous validation, you improved the functional capability of the patients of both groups A and B, that is in clinical premature and overdue stages. Conclusions. Significant improvement in the functional capability of patients affected of systemic sclerosis, with the medical treatment applied, with clinical stability and humoral from initial stages of the disease was caught up with.
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