Síndrome de Stevens-Jonhson secundario a dimenhidrinato en edad pediátrica
Abstract
El síndrome de Stevens-Johnson es una enfermedad inflamatoria aguda poco frecuente y grave, originada por una reacción de hipersensibilidad, secundaria a ingesta de medicamentos o infecciones, que afecta a la piel y las mucosas produciendo lesiones características de dermatosis reactivas con presencia de vesículas y/o ampollas, causadas por apoptosis de los queratinocitos. Su asociación con dimenhidrato es infrecuente.
Se presenta el caso de unaescolar de 9 años de edad, con diagnóstico clínico de síndrome de Stevens-Johnson, con manifestaciones cutáneas, oculares, genitales y de la mucosa oral, que iniciaron posterior a ingesta de dimenhidrato.Se mantuvo con un protocolo de cuidados que incluyeron la proscripción del fármaco y el inicio de medidas farmacológicas y no farmacológicas; tras 10 días de hospitalización la paciente evoluciona satisfactoriamente sin complicaciones durante su estancia hospitalaria.
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