Effects of chitosan on the healing process of wounds and burns
Keywords:
chitosan, healing, wounds, burnsAbstract
Introduction: Wound healing is a complex and constantly evolving technique, vital for tissue restoration and function. To reduce the impact of wounds and their care, an understanding of the healing mechanism is necessary. The use of natural polymers for biomedical applications is highly beneficial due to their high biocompatibility, biodegradation kinetics, and easy manipulation of chemical properties, among which is chitosan.
Objective: To delve deeper into the effects of chitosan on wound and burn healing.
Methods: A documentary review was carried out that included articles from journals indexed in PubMed/Medline, SciElo, Scopus databases and the Google Scholar search engine, in the period from March to December 2024, related to the effects of chitosan on wound and burn healing. 40 original articles were reviewed in the period 2018-2024, in Spanish and English, and 30 were referenced. The search terms included biomaterials, properties and effects of chitosan on wound and burn healing.
Development: Chitosan, a biopolymer derived from chitin, is an emerging biomaterial in wound and burn healing due to its biocompatibility, biodegradability, affinity with biomolecules, and healing activity. It exhibits healing capacity by accelerating the development of new skin cells, reducing inflammation, and preventing infections.
Conclusions: Chitosan is an effective biomaterial for healing and repairing tissue in wounds and burns.
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