Wunderlich Syndrome associated with Warfarin use

Authors

Keywords:

oral anticoagulant, nephrectomy, hematuria

Abstract

Introduction: Wunderlich syndrome is described as spontaneous renal hemorrhage or hemorrhage of non-traumatic origin. It is a rare and often fatal entity. Objective: To present a case of Wunderlich syndrome associated with the use of oral anticoagulants.

Objective: To present a case of Wunderlich syndrome associated with the use of oral anticoagulants.

Clinical case: A 77-year-old male patient with a personal pathological history of arterial hypertension, ischemic heart disease and atrial fibrillation treated with warfarin, without adequate control. The patient went to the emergency room with right lumbar pain of the colic type, of two days of evolution with irradiation to the right flank, iliac fossa and hemiscrotum, associated with hematuria, sweating and chills, without noting fever, and marked decay and general malaise. She denies a history of trauma and other urinary symptoms. Signs of hypovolemia associated with pain are observed.

Complementary tests are indicated where retroperitoneal hematoma is found in relation to Wunderlich syndrome. A conservative approach was maintained and as the general condition deteriorated, it was decided to perform emergency surgical treatment where, when addressing the retroperitoneal area, a perirenal hematoma was found in relation to the lower pole of the right kidney. A right nephrectomy was performed. In the histological study, no anatomical cause was defined. Conclusions: Wunderlich syndrome is a rare entity, but it can be fatal if not treated in a timely manner. Treatment depends on the patient's hemodynamic status.

Conclusions: Wunderlich syndrome is a rare entity, but it can be fatal if not treated in a timely manner. Treatment depends on the patient's hemodynamic status.

Author Biographies

Eilen Carol Reyes Griñán, Universidad de Ciencias Médicas de la Habana. Facultad Victoria de Girón. Hospital CIMEQ.

Doctora en Medicina. Residente de Urología

Miriam Daymi Hernández Rech, Universidad de Ciencias Médicas de La Habana. Facultad Victoria de Girón. Hospital CIMEQ

Especialista en primer grado en MGI. Especialista en primer grado de Urología.

Gabriela Hernández Sánchez, Universidad de Ciencias Médicas de La Habana. Facultad Victoria de Girón. Hospital CIMEQ

Doctora en Medicina. Residente de Imagenología y Radiología.

Sigfredo Calzadilla Feijoo, Universidad de Ciencias Médicas de La Habana. Facultad Victoria de Girón. Hospital CIMEQ

Doctor en medicina. Residente en Urología

Luis Enrique Concepción Portales, Universidad de Ciencias Médicas de La Habana. Facultad Victoria de Girón. Hospital CIMEQ

Especialista en Cirugía General

José Antonio Jordan González, Universidad de Ciencias Médicas de La Habana. Facultad Victoria de Girón. Hospital CIMEQ

Especialista en Imagenología y Radiología

References

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Published

2024-11-04

How to Cite

1.
Reyes Griñán EC, Hernández Rech MD, Hernández Sánchez G, Calzadilla Feijoo S, Concepción Portales LE, Jordan González JA. Wunderlich Syndrome associated with Warfarin use. Invest Medicoquir [Internet]. 2024 Nov. 4 [cited 2025 Dec. 5];16(1):e897. Available from: https://revcimeq.sld.cu/index.php/imq/article/view/897

Issue

Section

Case presentation