Clinical and epidemic characterization of the illnesses hepatobiliares in pregnant
Keywords:
hepatobiliary diseases, pregnant women, transaminasesAbstract
Introduction: Liver diseases, as a complication of pregnancy, occur in around 3% of pregnant women; They range from insignificant biochemical alterations to severe liver failure.
Objective: To describe the clinical and epidemiological characteristics of hepatobiliary diseases in a group of pregnant patients.
Material and methods: A descriptive and retrospective study was carried out on 46 pregnant women, who met the inclusion criteria (diagnosis of liver disease concomitant with pregnancy, chronic liver disease concomitant with pregnancy, and pregnancy-specific liver disease); Cases with individual clinical history with insufficient data were excluded. The variables analyzed were: age groups, personal pathological history, liver diseases and laboratory tests. The results were expressed in absolute numbers and percentages.
Results: Hyperemesis gravidarum occurred in 26 (56.5 %) patients, followed by intrahepatic cholestasis of pregnancy (12; 26 %) and gallstones (10; 32.6 %) during pregnancy. There were 18 (39.1 %) pregnant women between 31-35 years old. The four patients with preeclampsia had elevated hypertransaminasemia (15.4 %), GGT (8.7 %), and total bilirubin (15.4 %). In the case of acute fatty liver of pregnancy, the two patients with this diagnosis showed alterations in all parameters (transaminases, GGT, FA and bilirubin).
Conclusions: Hyperemesis gravidarum and gallstones were the most common pregnancy-specific liver disease and hepatobiliary disease concomitant with pregnancy, respectively. There was a predominance of patients aged between 31-35 years. Transaminases were the laboratory parameter with the most effects in these diseases.
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